View Full Version : Grapefruits Can Treat Disease As Well As Pharmaceuticals Without The Side Effects

05-12-12, 10:22 AM
Natasha Longo (http://preventdisease.com)May 11, 2012

In the never ending saga of natural disease fighting foods beating out pharmaceuticals, the grapefruit is another power packed citrus fruit to add to the the list. It actually never really gets the credit it deserves for preventing disease. But it can and without the side effects caused by pharmaceuticals. Grapefruits can prevent weight gain, treat diabetes, lower cholesterol, fight cancer, heal stomach ulcers, reduce gum disease and even keep stroke and metabolic syndrome at bay.

Naringenin, an antioxidant which gives grapefruit its bitter taste, can do the same job as two separate drugs currently used to manage Type 2 diabetes, scientists said.

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05-12-12, 01:49 PM
Grapefruit can also fatally interfere with medications. It is listed as an inhibitor on the flockhart P450. Eg. Statins and grapefruit should never, ever mix.

05-12-12, 02:06 PM
Sam is correct about grapefruit juice interacting with medications.
Some more information from Harvard Medical School:

Grapefruit’s culprit chemical does not interact directly with your pills. Instead, it binds to an enzyme in your intestinal tract known as CYP3A4, which reduces the absorption of certain medications. When grapefruit juice blocks the enzyme, it’s easier for the medication to pass from your gut to your bloodstream. Blood levels will rise faster and higher than normal, and in some cases the abnormally high levels can be dangerous.

A variety of medications can be boosted by grapefruit juice; the table below lists some of the most important along with related drugs that are less likely to be influenced.

Grapefruit juice and medications

Drug category (major uses)

Medications substantially boosted by grapefruit juice

Generic name (Brand name)

Medications that have little or no interaction with grapefruit juice

Generic name (Brand name)

Calcium channel blockers (high blood pressure, angina)

Felodipine (Plendil)

Nifedipine (Procardia, Adalat)

Verapamil (Calan, Isoptin)

Diltiazem (Cardizem)

Amlodipine (Norvasc)

Statins (high cholesterol)

Atorvastatin (Lipitor)

Simvastatin (Zocor)

Lovastatin (Mevacor)

Fluvastatin (Lescol)

Pravastatin (Pravachol)

Rosuvastatin (Crestor)

Immunosuppressants (to prevent rejection of transplanted organs)

Cyclosporine (Sandimmune)

Benzodiazepines (anxiety, insomnia)

Diazepam (Valium)

Triazolam (Halcion)

Midazolam (Versed)

Flurazepam (Dalmane)

Clonazepam (Klonopin)

Other neurological and psychiatric medications

Buspirone (BuSpar)

Sertraline (Zoloft)

Carbamazepine (Tegretol)

Haloperidol (Haldol)

Trazodone (Desyrel)

Zolpidem (Ambien)

It doesn’t take much grapefruit juice to boost the levels of drugs that are susceptible. A single glass can produce a 47% reduction of the intestinal enzyme that regulates absorption. And because this effect of the juice wears off slowly, a third of its impact is still evident after 24 hours.

05-13-12, 05:11 AM
Thanks for that Islander and Reesacat. The only negative thing I ever heard about grapefruit was it was not good for arthritics. On the other hand, I heard it was helpful in preventing arthritis. Odd!

05-13-12, 07:56 AM
The citrus fruit that I have been taught as being not good for people with arthritis is the orange. Many people in my experience have provided anecdotal evidence that their arthritis symptoms immediately become worse if they succumb to the temptation to eat the delicious orange. Never heard that about the grapefruit.

05-13-12, 12:23 PM
Thanx Sam & Reesacat for bringing up the drug interaction, which had slipped my mind.