View Full Version : Depleted Brain Chemical Induced Depression

10-06-10, 11:37 PM
There have been some posts on other sites recently about Depression. The article on Mercola.com did not touch on Serotonin and Dopamine induced Depression and several posters to this asked about Chemical Induced Depression, without what I consider to be satisfactory replies.
Thought this might be a topic of interest here to compare experiences of taking Serotonin and \ or Dopamine Reuptake Inhibitors with Natural Remedies. There are a lot of us out here with this problem and I would be interested in your experiences with Zoloft etc. :(

10-07-10, 10:47 AM
I seem to be the only one here this morning so I''ll start.
I was diagnosed as clinically depressed one winter and given a script for Effexor, back in the day when I thought doctors knew it all. I took it for a few months and yes, my outlook did improve, but I became anorgasmic — one of the predictable side effects of SSRIs. When I reported this to my doc, he pooh-poohed it, said I just imagined it because I had read the package insert. Please! At any rate, I decided that living without orgasms was a life not worth living, so I tossed the pills. And I was fine.

In retrospect, I can see what happened. It was back in the day when I was running a 4-acre garden center full-time and had cut back my teaching schedule to fall semester only. So after the busy semester of lively classes and faculty lunch, followed by winter holiday season...BAM. Nothing. Day after winter day of solitude, seeding seeding seeding seeding seeding with public radio as my only companion. It wasn't so much depression as a mild let-down and period of adjustment. I used to go through it every year, and if I hadn't mentioned it to the doc at my annual physical, well, I wouldn't have had that valuable lesson.

I've recently finished a book, Comfortably Numb, that you'll find in the Recommendations Forum. He thinks SSRIs are placebos; no chemical evidence that they work, as I recall.

10-07-10, 12:13 PM
I've never been on anti-depressants. Many years ago during a nasty divorce compounded with the stressors of being a single parent and student amongst other things, my doctor suggested I go on Buspar. I refused.

Life was transitioning for me, and I needed to accept that. It was in flux, and I needed to adapt and accept. The last thing I needed was to be doped up on an anti depressant when I had a small child and my studies.

I used 'talk therapy' with one or two of my closest friends whom I trusted. At one point I sought the assistance of a counselor , but not for long (4 mths) as academic commitments and funds, did not allow.

We all soon determined what I had always known.

I did not need a drug, but just to give myself time to heal. Time to re-adjust, transition, and be kind to myself...

I believe that many people today are far to quick to run to the Dr. and get a script when they are faced with life's challenges. True, there are occasions when they are needed, but one's diet, lifestyle, and 'gut' needs to be firmly addressed as a long term solution. I am a great advocate for talk therapy by close friend, or need be psychologist and EXERCISE! :)

10-07-10, 12:24 PM
LabDoc, in talking with a lot of people going gluten-free I am hearing how their depression/anxiety is improving or even gone. If you have migraine headaches, there is an 80% chance you are gluten intolerant.
I have several friends who are off of prescription meds and the only thing they did different was go gluten-free.
It is something that is just emerging in the alternate health world, so the information might be new to you.

10-07-10, 12:35 PM
I agree with Reesacat. Since going gluten free about 2.5 months ago, I have lost weight, sleep much better, my migraines have gone, and so have a lot of general body aches. I think when one finds that the inflammation in the body is gone, one sleeps better, and sleeping better will definitely elevate the mood and allow for greater coping.:)

10-07-10, 02:51 PM
Dr Rodney Ford is a Coeliac/Gluten Intolerance specialist in New Zealand who has written a number of books on the subject. One of them called "Full of It", documents the connection between gluten and the brain. Check out his website. The book can be found in the "Shop" page.

10-07-10, 08:10 PM
Well I must admit i did think that all the talk about Gluten free was a bit of hype, but think I will now do some serious reading about it. Interesting point of physiology is that the gut produces serotonin. Wonder if there is a correlation between gluten in food inhibiting gut and brain serotonin?

10-07-10, 08:36 PM
A girlfriend of mine used to sell Zoloft, Xanax, and Viagra (ED) for Pfizer; she made $125K and worked like 5 hrs per day. She said that her best seller of the three was actually Xanax, and Zoloft sold almost as well.

Are you looking to take Zoloft?

I am not a fan of antidepressants nor benzos personally. Just my opinion.

10-07-10, 10:39 PM
Well I must admit i did think that all the talk about Gluten free was a bit of hype, but think I will now do some serious reading about it.

When I was first diagnosed I didn't understand the test results and my doc was looking at signs of low adrenalin; she didn't even know what gliadin was. Mellowsong was the one who asked to see the adrenal fatigue test results and pointed out the finding of moderate gluten intolerance. I've since been gluten-free; lost 10-12 pounds originally but seem to have reached a plateau. Not sure what to expect next. Do I feel different? Not really....But I know I'm doing my body good.

10-09-10, 11:03 AM
Samurai, Have been on Zoloft for several years. Tried coming off twice (supervised) with disastrous results. Have had many full blood work ups over the years with no significant abnormality in anything - however Gluten free may be worth a self experiment.

10-09-10, 11:26 AM
Hey Lab Doc,
Allow me to start by saying that I have absolutely no personal experience with SSRI's. However, as odd as it may seem, I do have personal experience with a hormone that annihilated my GABA. And, since Benzos (which I have taken only like 3 pills- of benzos- in my life) have the exact same consequences, I found respice with others that have suffered from the horrific withdrawals of Xanax, Valium, and others.
I have seen some dark days in hell as a result of some "innoxious" and "natural" (valium is natural as well) pills. And one of the sayings that I hold to my heart that I learned from a Benzo support group was, "The only way out, is through".
It is a personal decision to make: "Shall I continue to take this? Or, shall I learn a different way to live?". This is your decision my friend. And what a quandary it is!
If you do decide to get off of the Zoloft, search online for others that have been where you are, and have been successful. Also, is there a possiblility that if you get "professional help", would they simply put you on another drug? For example, for the alcoholic who is now physically dependent upon alcohol, cannot quit cold turkey. Delirium tremens can kill the patient, and the protocol for that is a benzo. In essence, more trouble.
I think that there are some sites devoted to Paxil and the withdrawals. From there, you may find some help, and support.
I wish you health and happiness.

10-09-10, 08:44 PM
I am going to try not to get on a bandwagon here or sound judgemental. Lab Doc, I was on various and sundry antidepressants and multiple other psychotropic meds for over 25 years. I believe those meds took a good portion of my adult life away. They did not help me. Docs said I was resistant to them and just kept changing or increasing the dose. When I decided to try and come off these meds I was on 80mg a day of Cymbalta. It took me many months to get off of it and many more months of brain zaps and mood swings. At one time, I was pouring it out of the capsules and removing minute amounts with a razor blade because it was so difficult to stop. They now know that SSRIs but especially the SSNRIs cause physical dependence. They are literally hell to get off. It took me only a few weeks to get off over nearly 300mg/day of morphine. It took 6 months to get completely off Cymbalta and nearly that much longer to be free of side effects from stopping it.

Being on a fixed income, I could not afford many of the supplements suggested so my choice boiled down to high dose fish oil and magnesium along with the high fat diet, gluten free etc. It was not easy by any means. I could not have done it without the help of certain people I actually met through VV. I have been completely free of psychotropic medication for nearly 3 years. I have normal ups and downs and went through a few months of what I would consider "major depression" last winter, but I came through it.

At the time, I had absolutely no knowledge of gluten or gluten intolerance. The chiropractor I'd started seeing pretty much advised a completely grain free diet so I jumped in and did it over night. I initially lost nearly 50lbs, migraines stopped as well as being able to stop the meds. I don't know if gluten free would help you but it sure wouldn't hurt to give it a try. 2 years ago, I did the adrenal stress index and gliadin (the protein in gluten that causes most of the problems) antibodies were fairly high even though it had been weeks since I'd had gluten. I hope you don't mind me throwing personal experience in here. Like I said, I never benefited from the drugs, some people do.

10-09-10, 09:09 PM
Just slightly off topic: on a recent article, Joe Mercola was insulting and demeaning posters who claimed to have been helped through severe depression by psychoactive meds. While some posters, of course, agreed with him that it was possible to alleviate depression through natural approaches like diet and exercise, a significant number said essentially that SSRIs and other meds had literally saved their lives or kept them out of institutions. He dismissed them rudely and accused them of not having watched the video interview.

Well, I read the transcript, and the journalist (Whittaker) says very plainly that 1% of the severely depressed simply will not recover without medical intervention...a statistic JM conveniently forgets. Yes, I pointed that out to him. He probably won't see it now, he will have moved on, but that fact is that he's constantly brushing people off this way. I've lost all respect for him.

10-09-10, 10:58 PM
That 1% of the population who needs the prescription meds sounds about right-no one protocol is 100% effective and there are always those individuals with a genetic glitch that can't process/form/utilize something and need medical help.

Dr. Mercola should understand that by now.