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As far as I know, epigenetic tags transmit for three generations; potentially, they could last longer, but I'd expect their effects to be weakened as gene mixing increases with successive matings. Of...

Interestingly, bad genes do persist; there's just a high mortality rate of infants and young children. Among the San, over In subsistence populations, 40% of children may die before puberty. But...

Two things: it doesn't take a million years for genetic changes to take effect. In extreme conditions - like the Dutch winter - one generation is all it takes. In less extreme conditions -like...

Rich maternal diet may well be a factor in good vision in hunter-gatherers. Another may be natural selection. The myopic kids would be much more likely to step on scorpions, fail to see snakes, fall...

Arthritis in dinosaurs:
http://www.sciencemag.org/news/2016/08/70-million-years-later-duck-billed-dinosaur-has-diagnosis-septic-arthritis...

Here's some interesting stuff about arthritis:
https://www.ncbi.nlm.nih.gov/m/pubmed/26721908/
http://ngm.nationalgeographic.com/ngm/data/2001/11/01/html/ft_20011101.5.fulltext.html...

Osteoporosis can be caused by a number of factors. Calcium alone won't prevent it. A shortfall in phosphorus or selenium of any one of the other important nutrients will cancel out calcium intake. If...

Re obesity: yes, fat women would have been less agile than thinner women. But there are a couple of things to consider! Even obese women manage to get through an astounding amount of physical labour....

Osteoporosis is another very longstanding problem. I remember reading about the find of a skeleton, around 12,000 years old. It was that of a young man around 20 years old. He had such severe...

Obesity has been part of the human condition since the Upper Palaeolithic. For my undergraduate honors thesis, I looked at the artwork commonly called Venus figurines. Several of these depict women...

Getting back to inherited trauma: my great grandmother was incarcerated in a British concentration camp during the AngloBoer War. Two of her children died there. My grandmother was born in the camp....

I'm still feeling good. I had a therapy appointment yesterday, and discussed the situation with my therapist. She asked how I would feel if my mother died and we'd never spoken again. I thought about...

This is a good overview of inherited trauma: http://tedx.amsterdam/2014/08/trauma-can-inherited/

There's quite a lot of work being done in this aspect of depressive disorders....

I think that abuse is at least part of the problem for some of us; given the ongoing research into epigenetics and inherited trauma, even people who themselves have not been abused or experienced...

a very disappointing article! What does "many" mean? What percentage of depressives had high levels of inflammation markers? This report looks very much like confirmation bias in action.

This is...

It has occurred to me before that the negging on that other site may well involve moderators, simply because of the speed and size of the negs. To my mind, moderators should have their like/dislike...

I think there may be some misunderstanding of peer review: there are two kinds of peer review, short-term and long-term. I'm an archaeologist who has worked at editorial level on two journals, and...

Despite the dark money, there's a lot of good science being disseminated! Every time dark money is brought to light, good science is strengthened. The loudest whistle-blowers in dark money are...

Hmmm. To me, the fact that these errors are being caught, and retractions made, is good news. A public retraction of an article is serious, and puts a black mark against the name of the reviewer....

It might be better to know your mitochondrial haplotype than your genotype for Alzheimer's risk:
http://biology-web.nmsu.edu/~houde/mtDNAhaplogroupriskforAlzheimers.pdf...

https://m.youtube.com/watch?v=QyoPtGtQvHI

5 depression biotypes, according to William Walsh. I started watching this, am about 1/3 of the way through, and I think he may be on to something!

I’m coming into this from a different angle. Before I go into why I think that vaccines are (generally) a good thing, I would like to point out that pro-vaxxers are frequently attacked by...

Re sun and vitamin D: I grew up in sunny Southern Africa, farmed, gardened, and walked long distances. I wore shorts, tank tops, flip flops. and my hat. I was outside most of the day. I was...

I'd forgotten SAM-e! I lasted only a few days on it: it made me dizzy and so anxious that it felt as if my skin was crawling.

I think we need to differentiate between situational and endogenous depression, without making value judgements. I think the long-continued situational depression can become somatized, making it a...