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Thread: Fibromyalgia Brain Differences

  1. #1
    Administrator Islander's Avatar
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    16th September 2007
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    Default Fibromyalgia Brain Differences

    Jon Barron

    Fibromyalgia is a condition that produces chronic bouts of pain and fatigue in those who suffer from it. Even getting to a diagnosis of fibromyalgia can take a long time, as doctors often misdiagnose the problem with one of several other ailments that can cause similar symptoms. It is a difficult road for most fibromyalgia patients, since the pain can be debilitating, treatment measures are helpful only in reducing the discomfort, and no cure currently exists. As we discover more about fibromyalgia, though, there may eventually be a successful way to stop it entirely--or at least do a better job at reducing the pain. To that end, new research has made a breakthrough by discovering abnormalities in the brains of those with fibromyalgia that may begin to explain how they process pain differently from others without the disease.

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    Veteran Member Aaltrude's Avatar
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    2nd November 2008

    Default Re: Fibromyalgia Brain Differences

    I found this part of the article interesting.
    The resultant scans revealed that those subjects with fibromyalgia all had blood flow abnormalities within the vascular networks of their brains--collectively called brain perfusion--that were not present in the control subjects in the experiment. What's more, these differences to the brain were more substantial in those patients who exhibited the most pronounced symptoms. The scans also showed that the affected region of the brain was the area that is responsible for our ability to classify the intensity of any pain we are feeling.
    Dr Pall has theorised that an upregulation of the NO/ONOO- pathway in the area of the brain responsible for the perception of pain is responsible for the pain felt by Fibromyalgia sufferers. While this doesn't prove his theory it is consistent with it.

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