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Thread: Could A Mitochondrial Enhancer Replace Cymbalta in Fibromyalgia?

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    Veteran Member Reesacat's Avatar
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    Default Could A Mitochondrial Enhancer Replace Cymbalta in Fibromyalgia?

    Cort Johnson
    April 11, 2015

    How a Mitochondrial Booster Became an Antidepressant

    Acetyl0 L-carnitine (ALCAR) is best known as an energy supplement and mitochondrial booster the but folks in this fibromyalgia clinical trial were looking for more than increased energy; they were looking for relief from pain and depression as well. They pinned ALCAR not as an energy booster per se, but as a central nervous system protectant – and they had good reason to do so.Clin Exp Rheumatol. 2015 Mar-Apr;33(1 Suppl 88):82-5. Epub 2015 Mar 18. A randomised controlled trial comparing duloxetine and acetyl L-carnitine in fibromyalgia patients: preliminary data. Leombruni P1, Miniotti M1, Colonna F1, Sica C1, Castelli L2, Bruzzone M3, Parisi S3, Fusaro E3, Sarzi-Puttini P4, Atzeni F5, Torta RG1.

    Acetyl L-carnitine
    Acetyl- L-carnitine’s (ALCAR) transport of the important metabolic factor Acetyl CoA into the mitochondria increases energy production. Similar in structure to acetylcholine, it also stimulates acetylcholine production and enhances cellular membrane health.
    To read the rest of the article go to:
    http://www.cortjohnson.org/blog/2015...-fibromyalgia/

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    Veteran Member Maurya's Avatar
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    Default Re: Could A Mitochondrial Enhancer Replace Cymbalta in Fibromyalgia?

    "The study may also have underestimated the effects ALCAR can have when given in conjunction with other nutrients. Kaiser, for instance, asserts ALCAR is much more effective when used with alpha lipoic acid and NAC."

    Sound familiar? Synergy, or the whole is greater than the sum of its parts.

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