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Thread: Can Cholesterol Go Too Low?

  1. #1
    Administrator Islander's Avatar
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    Default Can Cholesterol Go Too Low?

    This is a long, detailed and thoroughly referenced article. If you're a tl;dr type, the short answer is Yes.

    Jon Barron
    04/01/2017

    Perhaps you saw the headlines.
    "Evolocumab significantly reduces risk of cardiovascular events." Science Daily1
    "New drug shows promise in preventing heart attacks." NHS Choices2
    "Evolocumab Added to Statins Cuts CV Events." Medscape3
    Very impressive at first glance, but what are those lines from Gilbert & Sullivan's HMS Pinafore?
    Things are seldom what they seem,
    Skim milk masquerades as cream;
    Very true,
    So they do.
    As it turns out, when we look at the study in question, it seems that we may have been Pinafored.

    Read more: https://jonbarron.org/heart-health/c...ol-go-too-low#
    ➤ Happiness is the frosting on the cake of contentment.

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    Veteran Member Maurya's Avatar
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    Default Re: Can Cholesterol Go Too Low?

    Excellent article, especially the conclusions and solutions sections. Here is one paragraph that sums up some of the salient points about this drug:

    "Low levels of LDL cholesterol have been associated with an increased risk for depression,8 higher mortality rates, especially in the elderly9--and suicide.10 Even more interesting is a study just published in the Journal of Affective Disorders that found an association between high levels of HDL (you know, the "good" cholesterol) and increased levels of depression and suicidality.11 Try telling that to your doctor."

  3. #3
    Administrator Islander's Avatar
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    Default Re: Can Cholesterol Go Too Low?

    Excellent points. Thank you for calling our attention to them.
    ➤ Happiness is the frosting on the cake of contentment.

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