Adrian L Lopresti & Peter D Drummond
January 1 2017


  • •Curcumin and saffron effective for the treatment of depression.
  • •Curcumin and saffron effective in reducing anxiety in depressed adults.
  • •Varying doses had no effect on outcome.
  • •Curcumin and saffron have greater efficacy for atypical depression.



Several studies have supported the antidepressant effects of curcumin (from the spice turmeric) and saffron for people with major depressive disorder. However, these studies have been hampered by poor designs, small sample sizes, short treatment duration, and similar intervention dosages. Furthermore, the antidepressant effects of combined curcumin and saffron administration are unknown.

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