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Thread: U of U research shows high altitude affects depression rates

  1. #1
    Veteran Member grulla's Avatar
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    Default U of U research shows high altitude affects depression rates

    ERIN COX
    JUNE 24, 2018

    SALT LAKE CITY — New research from two University of Utah professors’ show high altitude affects depression and the effectiveness of antidepressants. Professors of Psychiatry Perry Renshaw and Shami Kanekar said living at high altitudes means you are exposed to lower levels of oxygen, making it harder for your body to create serotonin—a neurotransmitter that is believed to regulate moods and behaviors.
    “Our work suggest that it really is the thin air that oxygen doesn’t do something directly, but it changes brain chemistry in ways that really change how we feel about things,” Renshaw said.
    For those who have a family history of depression or anxiety, Renshaw said, they are more susceptible to lower levels of serotonin. But the research goes further.

    Read on at: http://fox13now.com/2018/06/24/u-of-...ression-rates/
    Last edited by Islander; 06-25-18 at 08:59 PM.

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    Veteran Member grulla's Avatar
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    Default Re: U of U research shows high altitude affects depression rates

    Well, I live at 6300' elev, (1920.24 meters) and so far, so good. Usual everyday headaches and hassles aside, I'm happy as a clam. Cheers. :-)

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    Veteran Member Maurya's Avatar
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    Default Re: U of U research shows high altitude affects depression rates

    I live at about 170 feet elevation. Life is good!

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    Veteran Member Mr. Wizard's Avatar
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    Default Re: U of U research shows high altitude affects depression rates

    There's got to be more to this study. Most of the serotonin (90 to 95 percnet)--essential for depression--is made in the gut by endocrine cells. Less than 10 percent of serotonin is made in the brain by neural cells. So, it's curious to me why the body would not compensate for the decreased serotonin production in the brain by just increasing the amount produced in the gut. The gut-brain axis would surely signal a need to produce more. My understanding is that the serotonin produced in the gut is molecularly the same as that produced in the brain. The body is too smart not to compensate for the impact of oxygen at high altitudes. I need to dig deeper on this one. Intrigued!!

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    Moderator Julieanne's Avatar
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    Default Re: U of U research shows high altitude affects depression rates

    Wow Mr wizard, what a great observation! Let us know what you come up with.

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    Veteran Member Mr. Wizard's Avatar
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    Default Re: U of U research shows high altitude affects depression rates

    After several hours of research, it appears the $64,000 question is "how does gut serotonin affect the brain's function and behavior?" According to Dr. Elaine Hsiao, a researcher at the University of California, Los Angeles (UCLA) who studies how gut cells link to the brain, no one knows exactly how gut-based serotonin affects brain development and behavior. She and her colleagues around the world are still looking for an answer.
    Read more here: http://www.gutmicrobiotaforhealth.co...-elaine-hsiao/

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    Administrator Islander's Avatar
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    Default Re: U of U research shows high altitude affects depression rates

    Such dedication! Thank you for doing the painful work of research, Mr. Wizard. Since your reward is the disappointing "We don't know," I am honoring you with HH's distinctive medal of honor, the Above and Beyond Award. Wear it with pride — you have surely earned it!
    ➤ Happiness is the frosting on the cake of contentment.

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