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Thread: Valproate Linked to Decreased Brain Volume in Children Diagnosed with Bipolar Disorde

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    Administrator Islander's Avatar
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    Default Valproate Linked to Decreased Brain Volume in Children Diagnosed with Bipolar Disorde

    Zenobia Morrill
    August 9, 2018

    Researchers find that valproate decreases brain volume in a region associated with emotion processing across all participants

    A recent study led by researchers at the The University of Texas Health Science Center at Houston examined the effects of the drug valproate on brain volume in children diagnosed with pediatric bipolar disorder. Their findings, published in Psychiatry Research: Neuroimaging, demonstrate that brain volume decreased in the amygdala, a region associated with emotion processing functions, over a six-week period.

    Sodium valproate (VPA), commonly marketed under the brand names Depakote and Epilim, is a drug prescribed to individuals diagnosed with bipolar disorder. While some studies suggest that valproate is associated with protective factors and plasticity in the brain, others do not support this finding. Trials conducted on animals have found that valproate may decrease brain cell growth in regions associated with memory and lead to cognitive impairment.

    Keep reading: https://www.madinamerica.com/2018/08...olar-disorder/


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    Moderator Julieanne's Avatar
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    Default Re: Valproate Linked to Decreased Brain Volume in Children Diagnosed with Bipolar Dis

    If this showed up after only six weeks, one wonders how long the manufacturer tested this before putting it on the market?

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