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Thread: Scientists Race To Improve 'Living Drugs' To Fight Cancer

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    Administrator Islander's Avatar
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    Default Scientists Race To Improve 'Living Drugs' To Fight Cancer

    Rob Stein
    August 16, 2018

    Aaron Reid is lying in a hospital bed at the National Institutes of Health Clinical Center when doctors arrive to make sure he's ready for his experimental treatment.
    "How's your night? Any issues?" asks Dr. Katherine Barnett, a pediatric oncologist, as they begin to examine Reid.
    Reid, 20, of Lucedale, Miss., has been fighting leukemia since he was 9 years old. He has been through chemotherapy and radiation twice, a bone marrow transplant and two other treatments.
    But the leukemia keeps coming back. This time, the cancer is all over his body. He can feel the pain in his bones. He's in Bethesda, Md., for what could be his last hope.
    "The big plan for the day: Get the cells," says Dr. Andrea Gross, another pediatric oncologist.
    The cells are an experimental version of a relatively newcancer therapy called CAR-T.These CAR-T cells are sometimes called "living drugs" because they are engineered from patients' own immune system cells.

    Keep reading: https://www.npr.org/sections/health-...m_term=nprnews
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    Veteran Member Mr. Wizard's Avatar
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    Default Re: Scientists Race To Improve 'Living Drugs' To Fight Cancer

    Wishing Aaron Reid all the luck possible. I just wonder about the integrity of his immune system cells, given he's been through chemo & radiation twice, a bone marrow transplant and other treatments. It seems his CAR-T cells would be all but shot after more than a decade of radical leukemia treatments. Again, all the best to Aaron!!

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    Default Re: Scientists Race To Improve 'Living Drugs' To Fight Cancer

    I wonder, too, about the supposed efficacy of these "last resort" drugs that are administered after all other attempts have failed. Can their value really be quantified when they are introduced to an immune system already exhausted?

    And when was the last time anyone heard of IV vitamin C being injected in the fight against cancer?
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    Veteran Member Mr. Wizard's Avatar
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    Default Re: Scientists Race To Improve 'Living Drugs' To Fight Cancer

    You raise an excellent point about IV vit. C. As I know you know, the use of high-dose intravenous vit. C dates back to the work of Dr. Linus Pauling in the '70s. The therapy kills cancer cells without significant side effects, and most importantly, it doesn't kill normal cells. A 2014 University of Kansas Medical Center study showed that IV vit. C also made chemo more effective and eliminated some of the nasty side effects from chemo. As you know, IV vit. C is not covered by most health insurance and can get a little expensive. But, the real hurdle to obtaining this effective therapy is finding a doc, hospital, or a healthcare practitioner who will provide the therapy. I like that you occasionally bring up IV vit. C. Please keep reminding us that this effective and natural therapy exist.

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