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Thread: Antidepressant Drugs Work According to Latest Study: A Critical Re-Appraisal

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    Administrator Islander's Avatar
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    Default Antidepressant Drugs Work According to Latest Study: A Critical Re-Appraisal

    Michael P. Hengartner, PhD
    Oct. 24, 2018


    Dozens of meta-analyses including hundreds of antidepressant drug trials have been conducted to date. With a few notable exceptions 1 2, the vast majority of these meta-analyses conclude that antidepressant drugs are efficacious for major depressive disorder.3 4 Mainstream psychiatry constantly advises the public that antidepressant drugs work and that many more of them should be prescribed to people with major depression. The most recent meta-analysis by Cipriani and colleagues3 attracted a lot of public attention and several key opinion leaders made the bold claims in the media that “antidepressants clearly work in most people with depression.” However, paradoxically the massive increase in antidepressant prescription rates over the last three decades did not translate into measurable public health benefits,5 6 7 and various authors stated that the drugs don’t work at all.8 9 10 11

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    Veteran Member Mr. Wizard's Avatar
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    Default Re: Antidepressant Drugs Work According to Latest Study: A Critical Re-Appraisal

    This is a most controversial issue. Friends and relatives tell me antidepressants work for them. Yet, I read study after study that contradicts what people tell me. In the final analysis, I believe it's a matter of a placebo vs. nocebo effect.
    Last edited by Mr. Wizard; 1 Week Ago at 02:30 PM.

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