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Thread: Association of vit. B-6, folate, & vit. B-12 with depressive symptoms among adults

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    Administrator Islander's Avatar
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    Default Association of vit. B-6, folate, & vit. B-12 with depressive symptoms among adults

    Kimberly A Skarupski, Christine Tangney, Hong Li, Bichun Ouyang, Denis A Evans, and Martha Clare Morris
    Am J Clin Nutr. 2010 Aug; 92(2): 330–335.
    Published online 2010 Jun 2. doi: 10.3945/ajcn.2010.29413

    Background: B-vitamin deficiencies have been associated with depression; however, there is very little prospective evidence from population-based studies of older adults.
    Objective: We examined whether dietary intakes of vitamins B-6, folate, or vitamin B-12 were predictive of depressive symptoms over an average of 7.2 y in a community-based population of older adults.
    Conclusion: Our results support the hypotheses that high total intakes of vitamins B-6 and B-12 are protective of depressive symptoms over time in community-residing older adults.

    Read the details: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904034/
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    Veteran Member Mr. Wizard's Avatar
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    Default Re: Association of vit. B-6, folate, & vit. B-12 with depressive symptoms among adult

    Yes. B-vits. in general are known for their impact on our nerves, our mood, and our overall general disposition. They are also referred to by some as "stress relievers." Relief from depressive symptoms has been associated with vit. B-12 specifically. Research shows that some people only achieve relief from depression if both active forms of B-12 are used. Methylcobalamin is the one "active" form of B12 that's sold in most B vitamins. However, its twin--adenosylcobalamin--is the other active form that may be needed by those who don't get relief from just methylcobalamin. There are supplements that combine both active forms of B-12.

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    Default Re: Association of vit. B-6, folate, & vit. B-12 with depressive symptoms among adult

    Thanks for that useful info, Mr. Wizard!
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