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Thread: Study: Cholesterol-Lowering Statin Drugs Associated with Increased Shingles Outbreaks

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    Administrator Islander's Avatar
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    Default Study: Cholesterol-Lowering Statin Drugs Associated with Increased Shingles Outbreaks

    April 17, 2019
    Paul Fassa

    A recent meta-analysis review study looked into the association of cholesterol-lowering statin drug use with herpes zoster or shingles outbreaks, and determined there was a strong association of higher risk of shingles for older people who take statin drugs.
    Herpes zoster, more commonly known as shingles, is a painful skin irritation marked by rows of small sores with tiny blisters. It often strikes people over 50 who have experienced chickenpox during childhood.
    It’s suspected that this occurs when one’s cellular immune system is lowered enough to allow activating the dormant varicella virus (chicken pox) remaining after an earlier recovery from it.

    Keep reading: https://healthimpactnews.com/2019/st...les-outbreaks/
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    Veteran Member Mr. Wizard's Avatar
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    Default Re: Study: Cholesterol-Lowering Statin Drugs Associated with Increased Shingles Outbr

    Very interesting!! As I suspected, the study could not determine the mechanics of how statins actually activates the shingles virus. I wouldn't be surprised to learn that it's not the statins per se, but the effect of lowering cholesterol. In other words, a certain level of cholesterol is needed to keep the shingles virus at bay. Lowering cholesterol below a certain level, via statins, may be responsible for the re-activation of the virus. The liver produces cholesterol, which is critical for so many functions, including the synthesis of all major hormones, bile acid, digestive enzymes, Vitamin D, and so much more. There's no such thing as "bad" cholesterol. It's all good and necessary.

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    Default Re: Study: Cholesterol-Lowering Statin Drugs Associated with Increased Shingles Outbr

    That (the lowering of cholesterol) might be the key after all — good point!
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