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Thread: Potentially Deadly Heart Rhythm Disturbance - Chloroquine, Covid-19

  1. #1
    Moderator Julieanne's Avatar
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    Default Potentially Deadly Heart Rhythm Disturbance - Chloroquine, Covid-19

    Full Title: First Known Case Of A Potentionally Deadly Heart Rhythm Disturbance Induced By Chloroquine Therapy Reported

    Elsevier
    June 18 2020

    A patient who met many of the published safety guidelines for chloroquine therapy against COVID-19 was observed to have a very abnormal ECG pattern after treatment began, leading to multiple episodes of torsade de pointes (TdP), a life-threatening arrhythmia in which the lower chambers of the heart beat out of sync with the upper chambers. Her condition was resolved after chloroquine was discontinued

    Read more: https://www.sciencedaily.com/release...0618120201.htm
    Last edited by Julieanne; 06-24-20 at 07:50 AM.

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    Administrator Islander's Avatar
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    Default Re: Potentially Deadly Heart Rhythm Disturbance - Chloroquine, Covid-19

    You can see from the reference (2019) that this information is not new. Despite the fact that the president took a course of hydroxychloroquine, it has since been determined that the number and severity of side effects disqualify it as an appropriate treatment for COVID-19.
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    Veteran Member Mr. Wizard's Avatar
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    Default Re: Potentially Deadly Heart Rhythm Disturbance - Chloroquine, Covid-19

    Bayer invented chloroquine in 1934 to treat malaria. Hydroxychloroquine--invented during WWII as an alternative with fewer side effects--has been FDA approved to treat malaria, lupus and rheumatoid arthritis. FDA recently withdrew its emergency "hospital use" approval for COVID-19. I don't understand how a drug that's approved for other conditions causes heart conditions in COVID patients. In this article, the patient mentioned had a history of breast cancer, and was on hypertension and Alzheimer drugs. Perhaps, the additional drugs were as much the culprit as chlorquine???



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    Administrator Islander's Avatar
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    Default Re: Potentially Deadly Heart Rhythm Disturbance - Chloroquine, Covid-19

    IIRC, the advisory to discontinue the use of hydroxychloroquine to treat COVID-19 is not new. I remember seeing information somewhere, if not here than elsewhere online, that drew its conclusion from a much broader base of experiences with unwanted, unexpected side effects.
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    Veteran Member Mr. Wizard's Avatar
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    Default Re: Potentially Deadly Heart Rhythm Disturbance - Chloroquine, Covid-19

    Hydroxychloroquine medication can be purchased "without a prescription" in many African countries and Mexico, where it is used to combat malaria. When the U.S. president announced he was taking hydroxychloroquine as a COVID-19 prophalactic, the over-the-counter drug flew off the shelves in Mexico and many African countries. Likewise, U.S. pharmacies experienced as much as a 2-month backorder for the drug. I should stop here, lest I venture into the forbidden political realm.

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    Default Re: Potentially Deadly Heart Rhythm Disturbance - Chloroquine, Covid-19

    I am unable to read your mind or complete your thought, Mr. Wizard, but I do remember that because of the president's behavior, many Americans who have necessary prescriptions for malaria, lupus and other conditions treated by this drug, found it unavailable.
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    Veteran Member Mr. Wizard's Avatar
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    Default Re: Potentially Deadly Heart Rhythm Disturbance - Chloroquine, Covid-19

    A recent study published in the Journal of American Medical Association (JAMA) showed that in early 2020 there were almost 500,000 more prescriptions for hydroxychloroquine compared to early 2019. Keep reading here:
    https://jamanetwork.com/journals/jam...rticle/2766773
    Last edited by Islander; 06-28-20 at 09:35 AM.

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