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Thread: Common Class Of Drugs Linked To Increased Risk Of Alzheimer's Disease

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    Moderator Julieanne's Avatar
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    Default Common Class Of Drugs Linked To Increased Risk Of Alzheimer's Disease

    University of California - San Diego
    September 4 2020

    A team of scientists, led by researchers at University of California San Diego School of Medicine, report that a class of drugs used for a broad array of conditions, from allergies and colds to hypertension and urinary incontinence, may be associated with an increased risk of cognitive decline, particularly in older adults at greater risk for Alzheimer's disease (AD).
    The findings were published in the September 2, 2020 online issue of Neurology, the medical journal of the American Academy of Neurology.


    Read more: https://www.sciencedaily.com/release...0904125116.htm

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    Administrator Islander's Avatar
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    Default Re: Common Class Of Drugs Linked To Increased Risk Of Alzheimer's Disease

    This surprised me: "One-third were taking such medications, with an average of 4.7 anticholinergic drugs per person." In other words, a lot of people were taking more than four prescription drugs apiece. That's a lot of medicine. And the assumption is that they are taking more than one kind of drug, since everyone seems to be taking one or two prescription medications to begin with.
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    Moderator Julieanne's Avatar
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    Default Re: Common Class Of Drugs Linked To Increased Risk Of Alzheimer's Disease

    This is also worrying: "with 57 percent taken at twice the recommended dosage and 18 percent at least four times the recommended dosage."

    Here's a list of anticholergenic drugs:

    • atropine (Atropen)
    • belladonna alkaloids
    • benztropine mesylate (Cogentin)
    • clidinium
    • cyclopentolate (Cyclogyl)
    • darifenacin (Enablex)
    • dicylomine
    • fesoterodine (Toviaz)
    • flavoxate (Urispas)
    • glycopyrrolate
    • homatropine hydrobromide
    • hyoscyamine (Levsinex)
    • ipratropium (Atrovent)
    • orphenadrine
    • oxybutynin (Ditropan XL)
    • propantheline (Pro-banthine)
    • scopolamine
    • methscopolamine
    • solifenacin (VESIcare)
    • tiotropium (Spiriva)
    • tolterodine (Detrol)
    • trihexyphenidyl
    • trospium

    Although classified as an antihistamine to be taken for allergies and as a sleep aid, diphenhydramine (Benadryl) also has anticholinergic effects.

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