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Thread: In the Race for COVID-19 Vaccine, Slow Starters Could Still Win Out

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    Veteran Member Mr. Wizard's Avatar
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    Default In the Race for COVID-19 Vaccine, Slow Starters Could Still Win Out

    Helen Branswell
    September 24, 2020

    The race is not always to the swift, as the cocky hare learned in Aesop's classic fable, “The Hare and the Tortoise.” Those handicapping the so-called competition to develop Covid-19 vaccines would do well to keep an eye on the slower runners in this pursuit.
    Corporate giants Sanofi and Merck, which got a relatively late start in developing Covid-19 vaccines, may seem far behind the frontrunners. But experts say they also have such deep experience developing and testing vaccine candidates, and producing vaccine at commercial scale, that both could well close the gap considerably in the months ahead.

    Read more: https://www.statnews.com/2020/09/24/...still-win-out/


    Last edited by Islander; 4 Weeks Ago at 03:23 PM.

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    Veteran Member Mr. Wizard's Avatar
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    Default Re: In the Race for COVID-19 Vaccine, Slow Starters Could Still Win Out

    While reading this article, I was surprised to learn that a couple of vaccine manufacturers are making more than one type of vaccine, in case one type fails they have another in the hopper.

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    Administrator Islander's Avatar
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    Default Re: In the Race for COVID-19 Vaccine, Slow Starters Could Still Win Out

    We have already witnessed COVID-19 evolving into multiple strains, which makes me question how any single vaccine can possibly be any more effective than the annual fall flu vaccine that tries — and often fails — to target at least one prevailing strain for the coming season.
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    Veteran Member Mr. Wizard's Avatar
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    Default Re: In the Race for COVID-19 Vaccine, Slow Starters Could Still Win Out

    That's the million $$ question???? The short answer is no one knows. Experts agree the SARS-CoV-2 virus (an RNA virus) has mutated at least 14 times from the original strain. However, some argue that mutations can "weaken" the virus, while others argue mutations can make it more virulent. Adding to the confusion is the fact that while some mutations appear more virulent in the lab, that may not be the case in the body. Other experts claim that RNA viruses mutate all the time, like the measles, mumps, and rubella viruses, but mutations over the past 45 yrs. of these three viruses have not rendered the current vaccine ineffective. As long as the mutated virus retains enough of the original genetic code, a vaccine based on the earlier genetic code should remain effective,......they claim.
    Bottom line: if the mutations act like the mutations in other RNA viruses, like the measles, mumps & rubella, then a vaccine should remain effective. Conversely, if the mutations behave more like those of the annual flu virus, then the efficacy of a vaccine may prove fleeting. It's all an "educated guessing game" at this point!!
    Last edited by Mr. Wizard; 4 Weeks Ago at 02:47 PM.

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