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Thread: How the Oxford-AstraZeneca Vaccine Work

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    Default How the Oxford-AstraZeneca Vaccine Work

    Jonathan Corum and Carl Zimmer
    Jan. 8, 2021

    The University of Oxford partnered with the British-Swedish company AstraZeneca to develop and test a coronavirus vaccine known as ChAdOx1 nCoV-19 or AZD1222. A clinical trial revealed the vaccine was 62 to 90 percent effective, depending on the initial dosage. Despite some uncertainty over trial results, Britain authorized the vaccine for emergency use in December, and India authorized a version of the vaccine called Covishield on Jan. 3.
    The SARS-CoV-2 virus is studded with proteins that it uses to enter human cells. These so-called spike proteins make a tempting target for potential vaccines and treatments.
    The Oxford-AstraZeneca vaccine is based on the virus’s genetic instructions for building the spike protein. But unlike the Pfizer-BioNTech and Moderna vaccines, which store the instructions in single-stranded RNA, the Oxford vaccine uses double-stranded DNA.

    Keep reading: https://www.nytimes.com/interactive/...9-vaccine.html
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    New Member Swhealth's Avatar
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    Default Re: How the Oxford-AstraZeneca Vaccine Work

    I've read somewhere (maybe in other forum) that some people prefer the use of Oxford vaccine than of Moderna, I wonder why? I haven't seen any news lately about Moderna vaccine.

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